PHASE I STUDIES (national & international)

• First in man
  
  
• Pharmacokinetics and pharmacodynamics
  
  
• Food interactions
  
  
• Genotyping
  
  
• Coagulation factors
  
  
• Renal impairment

PHASE II-III B STUDIES (national & international)

Antiinfective drugs

Quinolones (gyrase inhibitors) / cephalosporins / macrolides
and ketolides

• Exacerbation of chronic bronchitis
  
  
• Acute bronchitis
  
  
• Pneumonia (CAP, HAP)
  
  
• Sepsis
  
  
• Otitis media
  
  
• Tonsillitis
  
  
• Urinary tract infection
  
  
• Maxilliary sinusitis
  
  
• Neutropenia

Asthma

• Acute asthma

Cardiovascular disease

• Coronary heart disease

Dementia

• Vascular dementia
  
  
• Alzheimer's disease

Dermatology

• Onychomycosis
  
  
• Brittle nail syndrome

HAE


HIV

Metabolic diseases

• Diabetes mellitus type I
  
  
• Diabetes mellitus type II
  
  
• Impaired glucose tolerance

Multiple sclerosis

• RRMS

Radiographic contrast media

• Patient with CAD

Renal impairment

Schizophrenia

Spinal cord injury

Vitamin C